Table 2 Characteristics of the included animal studies
From: Probiotics and eating disorders: a systematic review of humans and animal model studies
Studies | Country | Animal model | Sample size | Dose | Duration (Days) | Intervention | Outcomes | |
|---|---|---|---|---|---|---|---|---|
IG | CG | |||||||
Tennoune et al. 2015 [36] | France | Adult Male and female Wistar rats | 12 | 12 | 108 cells/mL Luria broth (LB) liquid medium | 21 | Escherichia coli K12 | Body weight, food intake, anti- α-MSH and ACTH immunoglobulin (Ig)G, fecal |
Trinh et al. 2023 [37] | Germany | Translational activity-based anorexia (ABA) female Wistar rats | 12 | 12 | 1 × 109 CFU/ml | 48 | VSL#3®: Bifidobacterium breve, Bifidobacterium longum, Bifidobacterium infantis, Streptococcus thermophilus, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, and Lactobacillus delbrueckii subsp. bulgaricus | Gut-Associated Lymphatic Tissue |
Nicol et al. 2023 [38] | France | C57Bl6 mice | 8 | 8 | 1 × 1010 CFU | 27 | mix of L. salivarius (LS) LS7892 and L. gasseri (LG) LG6410 | Sugar craving |
Chen et al. 2021 [39] | China | Mandarin fish (Siniperca chuatsi) | L. plantarum =270 L. rhamnosus=270 C. butyricum= 270 | 270 | 108 colony forming unit/mL to the culture water | 28 | Lactobacillus plantarum, Lactobacillus rhamnosus and Clostridium butyricum | Eating disorder characterized by food aversion and reduced feed intake when switched from their preferred live bait diet to an artificial pellet diet. |
Agusti et al. 2021 [35] | Spain | Wistar rats with food addiction | NR | NR | 1 ×108 colony-forming units of B. uniformis | 18 | Bacteroides uniformis CECT 7771 (B. uniformis) | Binge eating and anxiety-like behavior |